India's first proprietary postbiotic+74% stool butyrate in a CTRI-registered trial*n=90 members trackedFree shipping over ₹999One daily formula · 500 mg GTB™Backed by a 30-day promiseMade in a US FDA-registered facility*Conditions appliedIndia's first proprietary postbiotic+74% stool butyrate in a CTRI-registered trial*n=90 members trackedFree shipping over ₹999One daily formula · 500 mg GTB™Backed by a 30-day promiseMade in a US FDA-registered facility*Conditions applied
Third Biome
India's first postbiotic · Clinically tested · Made in India

Question the noise, trust the gut.

A proprietary postbiotic, Thirdbiome GTB™, engineered to reach your colon intact and work from the very first dose. No live bacteria to gamble on.

Shop Biome Balance See the evidence
+74%Stool butyrate
9/10Calmer by week 2
1Ingredient
CTRI-registered trial
Biome Balance postbiotic, floating tube with capsules
300+ T3B Club members · 4 cohortsFree shipping over ₹999US FDA-registered facilityCOD across IndiaRegistered, double-blinded RCTProprietary postbiotic
One ingredient
500 mg GTB™ per capsule
Free shipping ₹999+ · COD
Across India
US FDA-registered facility
WHO-GMP
30-day promise
Easy returns
Shop by goal

Designed around your biological systems

Foundational postbiotic support, calibrated to the systems that shape long-term gut health.

Shop all →
DigestionBloating & heaviness

Bloating & heaviness

Ease gas, bloating and irregular digestion

Biome Balance →
Gut-brainFocus & mood

Focus & mood

Clearer afternoons, steadier mood

Biome Balance →
DefenceImmunity & resilience

Immunity & resilience

Support the gut lining that guards you

Biome Balance →
BalanceCravings & metabolic

Cravings & metabolic

Calmer cravings, steadier energy

Biome Balance →
Start here

What exactly is a postbiotic
and how does it work for you?

Metabolic compounds produced by healthy bacteria that heal the gut lining are called postbiotics.

Stable and heat-tolerant, these compounds are bioavailable on arrival, delivering measurable results, unlike pre- and probiotics that depend on surviving and colonising first.

The 30-second finder

What's your gut working against?

Let's talk through how it really affects your life, click on any that apply.

See my recommendation Select what applies to personalise it.
A daily system, precisely applied

One ingredient. Several jobs.

Survives the journey
Systemic

Survives the journey

A pH-targeted capsule carries GTB past stomach acid, intact.

Releases at the colon
Bioavailable

Releases at the colon

Lipases free butyrate exactly where your gut lining needs it.

Repairs & calms
Evidence-led

Repairs & calms

Fuels colonocytes, tightens tight junctions, signals immune calm.

Built for daily use
Sustainable

Built for daily use

One capsule a day, formulated for consistency, not intensity.

GTB™ delivery technology

Most gut actives don't survive stomach acid, GTB™ does.

GTB armRaised stool butyrate74%

Registered, double-blinded RCT · 45 days · CTRI/2025/09/094597

A pH-targeted shell shields GTB™ from stomach acid through the digestive tract.

Releases butyrate at the colon, exactly where your gut lining needs it most.

Real-world stewardship

Tracked across our 30-day Club cohorts, documented week by week.

Reported less bloating
87%

Felt calmer digestion

Nine in ten members noticed a shift by the second week.

By week 2
9/10
Real guts, real results

How we help consumers.

Aravind
Aravind
46 · Male · 4 weeks
Chronic gas, bloating, gut-brain symptoms.
44%gas reduction
Subashan
Subashan
21 · Male · 3 weeks
Bloating & low energy on high-protein diet.
~100%energy increase
Alex
Alex
40 · Male · 1 month
Gas, urgency, bowel irregularity & anxiety.
71%gas · urgency resolved
Deepan
Deepan
20 · Male · 3 weeks
Bowel urgency, sugar cravings & acne.
57%craving drop
Chakradhar
Chakradhar
25 · Male · 30 days
Brain fog, bad breath & fatigue.
75%oral health
Karthikayan
Karthikayan
30 · Male · 30 days
Severe bloating, cravings & acne.
90%bloating drop
Shweta
Shweta
36 · Female · 30 days
Constipation, fasting headaches & mood.
80%irritability drop
Aravind
Aravind
46 · Male · 4 weeks
Chronic gas, bloating, gut-brain symptoms.
44%gas reduction
Subashan
Subashan
21 · Male · 3 weeks
Bloating & low energy on high-protein diet.
~100%energy increase
Alex
Alex
40 · Male · 1 month
Gas, urgency, bowel irregularity & anxiety.
71%gas · urgency resolved
Deepan
Deepan
20 · Male · 3 weeks
Bowel urgency, sugar cravings & acne.
57%craving drop
Chakradhar
Chakradhar
25 · Male · 30 days
Brain fog, bad breath & fatigue.
75%oral health
Karthikayan
Karthikayan
30 · Male · 30 days
Severe bloating, cravings & acne.
90%bloating drop
Shweta
Shweta
36 · Female · 30 days
Constipation, fasting headaches & mood.
80%irritability drop
Read all case studies →

All cases are single-participant, self-reported, and do not establish causality.

The science, in numbers

Seven things worth knowing.

Science fact
70%
of colon cell energy from butyrate

Your gut lining runs on one fuel. Most people are running on empty.

Colonocytes, the cells lining your gut, rely on butyrate for ~70% of their energy. GTB™ delivers it directly, bypassing stomach acid entirely.

Clinical literature on colonocyte metabolism
Real world evidence
87%
reported bloating reduction

In 30 days, members didn’t just feel better, they understood why.

Tracked across T3B Club stewardship cohorts. Real people, real gut protocols, documented week by week.

T3B Club 30-day cohort · Urban India · 2025-2026
Delivery technology
100%
stomach-acid protected

Most gut supplements never reach your gut. This one is engineered to.

Precision microencapsulation releases only at the colon, where your gut lining needs it. No degradation. Full potency.

Lipase-mediated hydrolysis · proprietary
30-day stewardship
Week 2
when members first feel a shift

Gut repair doesn’t happen overnight. But you’ll know it’s working.

The first real shift arrives around day 10-14. By day 30, over 70% choose to continue their protocol.

T3B Club stewardship cohort
Mechanism of action
3
pathways · 1 molecule

One ingredient. Three measurable actions inside your gut.

TNF-alpha inhibition (inflammation), tight junction synthesis (leaky gut), and GLP-1 activation (metabolic balance), one daily capsule.

Published research on Glycerol Tributyrate · 2025
India’s first

India didn’t have a postbiotic brand. We built one, with proprietary technology to prove it.

Third Biome is India’s first precision postbiotic ecosystem. FSSAI-approved. Proprietary GTB technology. Clinically designed.

16SKUs in pipeline
1stpostbiotic brand in India
+74%stool butyrate, GTB arm (RCT)
Feels considered. Built to last.

A system-level approach to gut health, designed for consistency, not intensity.

Why now

Gut care evolves with each generation.

You don't eat like your grandparents did, the diet, the pace, the food groups, it's all changed. But your gut still runs on ancient wiring. It needs a modern, measurable tool to keep up.

Founders / lab
Our story · Made in India (for the world)

We'd rather be right than loud.

Gut health is full of hype, strain counts no one can verify, claims with no mechanism. We're building the opposite: a brand you can fact-check, ingredient by ingredient.

  • US FDA-registered, WHO-GMP facility
  • CTRI-registered, double-blinded RCT
  • One ingredient
  • Proprietary technology
Probiotic vs postbiotic

The evolved move.

Question
Probiotic
Postbiotic · GTB™
Survives stomach acid?
Rarely, most strains die first
✓Micro-encapsulated to arrive intact
Needs an existing microbiome?
Yes, relies on your bacteria
✓No, acts as the finished metabolite
Has to colonise first?
Yes, results vary
✓No, works on arrival, in days
Consistent dose to dose?
Drifts with heat, storage, time
✓Defined 500 mg, every time
Honest evidence?
Often broad & strain-agnostic
✓Registered RCT, limits published
In their own words

Probiotic vs postbiotic, side by side.

Same questions, two very different answers. Tap to open each.

Probiotic

Not really. More often than not, we're killed en route before doing anything useful.

Postbiotic · GTB™

Always. There's nothing alive to kill, the compound is structurally stable and arrives intact.

Probiotic

It helps a lot. Native bacteria make survival and performance far more likely, without them, results suffer.

Postbiotic · GTB™

No difference. It's the finished end-metabolite, so it works independently of your existing gut flora.

Probiotic

Yes. Building up enough of every strain is necessary, and success isn't guaranteed, so results vary.

Postbiotic · GTB™

No. It's already the active compound, so it gets right to work on arrival, in days, not weeks.

Probiotic

It varies batch to batch, potency drifts with heat, storage and where the strain is in its 1-3 year lifespan.

Postbiotic · GTB™

Precise & consistent. Not alive, so it can't degrade, a defined 500 mg, every single dose.

Probiotic

We must ferment to survive, which can cause temporary gas, bloating and cramps as we settle in.

Postbiotic · GTB™

Gentle. Ready-to-use and inanimate, it skips the messy fermentation step entirely.

Real guts, real talk

Loved by early members

300+ members across 4 T3B Club cohorts, sharing honest results.

★★★★★

“The bloating eased in the first week, and I finally stopped feeling foggy by mid-afternoon.”

R
Riya M.
Verified · Mumbai
★★★★★

“What sold me was the honesty, they show the actual trial and its limits. Rare in this space.”

A
Arjun S.
Verified · Bengaluru
★★★★★

“One capsule, no 12-step routine. My digestion is finally predictable again.”

N
Neha K.
Verified · Delhi
Membership

The T3B Club

  • A doctor-guided, 90-day postbiotic protocol tailored to your gut.
  • Your Biome Balance, delivered monthly, never run out.
  • Weekly check-ins and the science in plain English.
  • Direct access to our medical team when you need a real answer.
Join the club
₹2,878 / 3 months
₹32/day · save 20% vs one-off
Start my protocol
Letters from the lab

Gut science,
plainly written.

Read the journal →
Gut Health

The Gut-Brain Axis: How Your Gut Controls Your Mood, Focus, and Energy

Brain fog, mood crashes, and afternoon fatigue may not be mental health issues. They may be gut issues. Here's the complete science of the gut-brain axis — and what Third Biome GTB does about it.

8 minMarch 2026
Gut Health

Feeling bloated after every meal? Discover What's Really Happening in Your Gut

If you're bloated after meals — even healthy ones — the problem is not the food. It is your gut microbiome. Here's the science and the postbiotic solution that is changing gut health in India.

7 minMarch 2026
Gut Health

Why Probiotics Fail 50% of the Time—And the Postbiotic Fix

Taken probiotics for months with little result? You're not alone. Here's the exact science of why probiotics often underdeliver for Indian guts — and what postbiotics like Third Biome GTB do differently.

7 minMarch 2026
Who we are
India’s 1stpostbiotic brand

We’d rather be right than loud.

Formulated by doctors. CTRI-registered trial. US FDA-registered facility. We publish our limits, not just our wins.

US FDA-registeredWHO-GMPFSSAIProprietary tech
Good questions

The honest FAQ

No. It's a postbiotic, the finished metabolite (butyrate, via Thirdbiome GTB™) your gut would normally make for itself. There are no live cultures to keep alive or hope will colonise.

Most people feel gas and bloating ease within the first week or two. Gut-brain and systemic benefits build over the season, think months, not days.

Yes. Thirdbiome GTB™ is built on our own proprietary technology. We describe it as proprietary, nothing we can't stand behind.

A registered, randomised, double-blinded RCT (CTRI/2025/09/094597) over 45 days. The GTB arm raised stool butyrate by 74%, with symptom scores significantly improving alongside.

Free guide + monthly letter

Get The Beginner’s Guide to Postbiotics, free.

Plain-English gut science, the GTB™ mechanism explained, a 30-day protocol starter, and ₹200 off your first order.

Free: The Beginner’s Guide to PostbioticsPDF · 18 pages · plain English

You're on the list ✓

We'll be in touch.

Biome Balance
₹1,199
India's first postbiotic

One ingredient. Nothing to hide.

Thirdbiome GTB™ reaches your colon intact and works from the first dose. One daily capsule, a registered RCT behind it, and a 30-day promise.

Shop Biome Balance →
See what it did for them →
Added to cart ✓